If you receive the error message “Failed to initialize rendering subsystem” then there are several potential causes.
First, this issue is typically the result of insufficient hardware for running the game. In such a case the only solution is to upgrade your system’s hardware.
If your system meets or exceeds requirements then please try changing your in-game resolution so that it matches the native resolution for your primary display.
Finally, please try using the Repair Broken Data tool in the launcher to see if this helps.
If none of the above solutions help then the only option remaining is a full reinstall of the game.