In the PvE servers, you are unlikely to meet with hackers or cheaters.
On the official PvE servers, no player can destroy your base, nor steal your items (be they stored in your thralls/mount, your own dead or alive body, chests, crafting stations). The only exception to that, is if they abuse of the game mechanics in ways they were not meant to be played. Even then, it is very unlikely to happen.
I had my fare share of jerk neighbours for a year and a half on the same official server, none of them abused of the system to destroy my base even when we were arguing. :+1:
My only advice: do not stick your base to a player’s base. Leave reasonable space in between.

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