The Brute is easy. Just accept some dmg and it goes down fast.
The snake is not difficulty per se. It’s the little ones you need to worry about before going for the big girl. You can’t stack poison. It kills you very fast, so you either have an antidote or you better have many potions. I got a locusts purge a little while ago and I went in there alone because they are very easy. The little green ones apply 4 stacks of poison super fast. They die in one hit, but I was cocky and just survived for a hair, chugging potions like mad after having 8 stacks of poison. Then I just didn’t let myself get bit. With the snake, you’ll be bit for sure. So yeah, that bitch is dangerous! 
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