Has anyone figured out now that the game has levels what are the zones by level? Can you quest in Blue Mountain at level 21?
You can do quest as much as you like as long as you have the minimum level. If that was the question.
You can only go 2 levels below the recommended amount, 3 below locks out missions & makes mobs kill you easily.
Executive summary of the above: mostly no, as the minimum level for missions is generally too high.