Yes you can, but you have to have a few mods in play for it to work. It does break the quest though, as the barrier by the throne never drops if you knock and break her. With the less bld restriction mod, you can drop a wheel in the room with her…
I was replying to the question about putting her on a wheel of pain - not knocking her out. There’s no way you can put her on a wheel, without the less building restrictions mod (since you can’t drag her out of the transition door, tmk.)