In addition to what @DeaconElie said, you can still loot chests from sepamaru, grab some tools from mounds of the dead, do journey steps and grab brimstone from sinners refuge, do whatever dungeon you can manage like dregs or silver mine for legendary weapons, farm red lotus and black ice for levels, then when ready farm unnamed city for breath of the red mother, reach of the red mother, maybe a predatory blade, and fragments of power.