Best Tool for Demon Blood?

I’m wanting to make some map rooms at my base and at some obelisks in single player mode. I get Ichor pretty easily with Unappetizing Fish from the Fish Traps I have around my base, and Stone is easy to get.
I know what I need to kill to get Demon Blood, but what would be the best tool to obtain it?

PickAxe

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30 survival (to get more from harvesting animals)
kill the set snake (can be found at arena and the temple of triumvirate in UC ) and use an obsidian pick with tool enhancement. i get over 200 in a single kill

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